That word you use ... "optimize", is on the players, not any special batch of plays you speak of. It's up to them.. to keep the proper flow to the offense by making the right decision and moving the ball. That, combined w the spacing is essentially our offense and it can be quite potent when run correctly.
Granted you do have slight variations where you look to get Melo the ball from 15, Amare the ball in the high-post, or when you look to run the high pick and roll w Billups/ TD, but the spacing is similar and the principles remain the same -- read quickly/ correctly take what the D gives, pass off of help if drawn, move it to the open man. Our offense is simple, but not easy to run due to the discipline and quick decision making involved. Guys need to be comfortable taking shots quickly too and that takes some getting used too it. TD's just recently come around completely to our principles as a scorer in this offense, which shows how long it takes to really get a feel for how to operate within the framework.
Melo is so good and so smart offensively that he seems to have a pretty good feel for it already. He looks really comfortable within our spacing from three. He likes that quick three too. He's thriving in this offense.